Table 1 Hemodynamics of Groups 1 and 2 at rest and exercise.

From: Comparison of device-based therapy options for heart failure with preserved ejection fraction: a simulation study

 

Group 1

Group2

Rest

Literature24

n = 24

Simulation

Literature16

n = 264

Simulation

EDV (ml)

93 (73–108)

100.1

143 ± 20

142.8

ESV (ml)

39 (31–60)

41.5

55 ± 18

52.0

EF (%)

59 (45–63)

58.6

65 ± 12

63.6

MAP (mmHg)

91 ± 10

93.4

105 ± 14

108.0

HR (bpm)

76 (64–84)

76.5

71 ± 9

70.0

RAP (mmHg)

6 (5–8)

6.3

6 ± 2

6.6

PAP (mmHg)

25(18–29)

26.7

19 ± 3

22.0

PCWP/LAP (mmHg)

15 (11–20)

16.5

15 ± 7

16.7

CO (l/min)

4.4 ± 1.1

4.5

6.26 ± 0.85

6.34

 

Exercise

Literature24

n = 24

Simulation

Literature16

n = 46

Simulation

EDV (ml)

–

114.5

158 ± 50

157.1

ESV (ml)

–

50.2

66 ± 45

63.3

EF (%)

–

56.2

58 ± 22

59.7

MAP (mmHg)

104 ± 28

108.5

123 ± 14

123.2

HR (bpm)

125 (105–141)

126.9

103 ± 14

102.6

RAP (mmHg)

14 (10–19)

17.3

14 ± 4

13.6

PAP (mmHg)

45 (40–52)

47.5

41 ± 6

32.9

PCWP/LAP (mmHg)

32 (25–35)

31.5

26 ± 4

25.0

CO (l/min)

7.7 ± 3.8

8.3

9.6 ± 2.0

9.70

  1. EDV end diastolic volume, ESV end systolic volume, EF ejection fraction, MAP mean arterial pressure, HR heart rate, RAP right atrial pressure, PAP pulmonary arterial pressure, PCWP pulmonary capillary wedge pressure, LAP left atrial pressure, CO cardiac output.
Back to article page