Table 1 Antiproliferative activity (IC50 value in μg/mL) of ethanol extract of Taxus Yunnanensis wood against proliferating cells.
From: Understanding of cell death induced by the constituents of Taxus yunnanensis wood
Cell line | Wood (ethanol extract) | Apoptosis |
|---|---|---|
Human tumor cell line | ||
SH-SY5Y (neuroblastoma) | 0.98 | + |
DU-145 (prostate carcinoma) | 1.92 | + |
PANC-1 (pancreatic carcinoma) | 0.81 | + |
T24 (urinary bladder carcinoma) | 2.62 | + |
MDA-MB-231 (breast adenocarcinoma) | 0.56 | + |
Rh30 (rhabdomyosarcoma) | 0.42 | + |
K562 (myelogenous leukemia) | 2.56 | + |
RPMI8226 (myeloma) | 1.2 | + |
DLD-1 (colorectal carcinoma) | 3.81 | + |
DLD-1/5FU | 3.46 | + |
DLD-1/OXA | 3.52 | + |
Non-cancerous cell lines | ||
ASF-4-1 (human fibroblasts) | 20.94 | – |
H9c2 (rat cardiocytes) | 50 < | – |
TIG-3-20 (human fibroblasts) | 2.89 | – |
HMEC (human mammary epithelial cells) | 50 < | – |