Figure 2
From: Heterogeneous fates of simultaneously-born neurons in the cortical ventricular zone
Isochronic early AP-born neurons are radially dispersed as they invade the cortical plate. (a–b) Position of isochronic E13.5-born (a) and E15.5-born (b) neurons from 1 to 9 days after FT injection (n = 3 pups/condition). Note the rapidly compact radial distribution of E15.5-born neurons compared to E13.5-born ones. Boxplots indicate mean and standard deviation of radial position. The radial position of cells in the CP was normalized by CP thickness at each embryonic age. (c) Summary of Standard Deviation of positions in the cortical plate for E13.5-born and E15.5-born neurons starting from the second day after injection. Lines indicate linear data integration, shades indicate 95% confidence interval. Scale bars: 50 µm (a, b). CP Cortical Plate; d day after injection; E Embryonic day; FT FlashTag; IZ Intermediate Zone; p1, p2, p3 Pup number.
