Table 4 Methodological quality assessment of the studies by Newcastle–Ottawa quality scale assessment (NOS).

From: Craniofacial morphology in Apert syndrome: a systematic review and meta-analysis

References

Selection

Comparability

Exposure

Total score

1

2

3

4

5

6

7

8

9

Kobayashi et al.34

*

*

*

*

*

*

*

*

–

8

Lu et al.23

*

*

*

*

*

*

*

*

–

8

Meazzini et al.35

*

*

–

*

*

*

–

*

–

6

Morice et al.32

*

*

–

*

*

*

–

*

–

6

Lu et al.26

*

*

*

*

*

*

*

*

–

8

Lu et al.24

*

*

*

*

*

*

*

*

–

8

Lu et al.25

*

*

–

*

*

*

*

*

–

7

Forte et al.33

*

*

*

–

*

*

*

*

–

7

Reitsma et al.30

*

*

–

*

*

*

–

*

–

6

Reitsma et al.29

*

*

–

*

*

*

–

*

–

6

Reitsma et al.31

*

*

–

*

*

*

*

*

–

7

Wink et al.27

*

*

–

*

*

*

*

*

–

7

Boutros et al.28

*

*

*

*

*

–

–

*

–

6

  1. 1—Adequate case definition; 2—Representativeness of the cases; 3—Selections of control/comparator; 4—Definitions of control/comparator; 5—case; 6—Control/ comparator; 7—Exposure of evaluation; 8—Same method for case and control; 9—Nonresponse rate.
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