Figure 1

miRNA Expression in Infants with NOWS Requiring Pharmacologic Treatment or Prolonged Hospitalization. Volcano plots of cord blood plasma extracellular miRNA expression (difference in normalized CT between groups, ΔΔCT) and effect size (Cohen’s d) comparing miRNA expression in neonates Pharmacologically-Treated compared to Not-Pharmacologically-Treated (A) and in LOS ≥ 14 days compared to LOS < 14 days neonates (B). White filled points denote miRNAs altered with a small effect size (d < 0.4), black filled points denote miRNAs with moderate or larger effect size (d > 0.4), and dashed line denotes d = 0.4.