Table 1 Clinical and ultrasonic features of the thyroid nodules.
Variables, n (%) | Benign (n = 74) | Malignant (n = 100) | p* | Odds Ratio (95% CI) | p§ |
|---|---|---|---|---|---|
Shape | |||||
Wider-than-tall | 68 (92) | 61 (61) | < 0.001 | 1 (reference) | 0.002 |
Taller-than-wide | 6 (8) | 39 (39) | 6.117 (1.936,19.322) | ||
Echogenicity | |||||
Isoechoic/Hyperechoic | 4 (5) | 10 (10) | 0.008 | 1 (reference) | 0.1 |
Hypoechoic | 53 (72) | 83 (83) | 3.546 (0.548–22.943) | 84 | |
Very hypoechoic | 17 (23) | 7 (7) | 1.816 (0.504–6.541) | 0.361 | |
Margin | |||||
Smooth | 46 (62) | 21 (21) | < 0.001 | 1 (reference) | |
Lobulated or irregular | 9 (12) | 38 (38) | 4.178 (1.511,11.552) | 0.006 | |
Ill-defined | 19 (26) | 41 (41) | 2.318 (0.942,5.706) | 0.067 | |
Echogenic foci | |||||
None | 23 (31) | 15 (15) | 0.016 | 1 (reference) | |
Punctate echogenic foci | 38 (51) | 74 (74) | 3.05 (1.096–8.490) | 0.033 | |
Macrocalcifications | 10 (14) | 7 (7) | 1.736 (0.406–7.429) | 0.457 | |
Peripheral calcifications | 3 (4) | 4 (4) | 4.354 (0.557–34.044) | 0.161 | |
Acoustis halo | |||||
None | 62 (84) | 96 (96) | 0.004 | 1 (reference) | |
Complete | 10 (14) | 1 (1) | 0.294 (0.03–2.842) | 0.290 | |
Interrupted | 2 (3) | 3 (3) | 3.648 (0.403–33.058) | 0.250 | |
Blood flow | |||||
None | 17 (23) | 41 (41) | 0.029 | 1 (reference) | |
Hypervascular | 30 (41) | 26 (26) | 0.768 (0.283–2.082) | 0.603 | |
Mild/moderate | 27 (36) | 33 (33) | 0.756 (0.305–1.871) | 0.545 | |
Posterior echo | |||||
None | 72 (97) | 90 (90) | 0.060 | ||
Attenuation | 2 (3) | 10 (10) | |||
Composition | |||||
Solid | 69 (93) | 97 (97) | 0.287 | ||
Mixed cystic and solid | 5 (7) | 3 (3) | |||
Age, years (mean ± SD) | 47 ± 14 | 44 ± 13 | 0.146 | ||
Gender | |||||
Male | 14 (19) | 29 (29) | 0.127 | ||
Female | 60 (81) | 71 (71) | |||
Diameter, milimeters (mean ± SD) | 18 ± 13 | 12 ± 7 | < 0.001 | ||
