Figure 3 | Scientific Reports

Figure 3

From: Manifestations of Alzheimer’s disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90

Figure 3The alternative text for this image may have been generated using AI.

Unadjusted box plots of normalized protein expression levels (NPX) of six proteins significantly associated with APOE2 genotype, by age group. White boxplots = individuals who are homozygous for the major allele, gray boxplots = heterozygotes, black boxplots = minor allele homozygotes. Box plot midline = median value, lower/upper hinges = 25th and 75th percentiles, respectively; lower whisker ends/upper whisker ends no further than 1.5× interquartile range from the hinge. Data beyond whiskers are outlying points. LDLR low-density lipoprotein receptor, HMOX1 heme oxygenase-1, SLAMF8 SLAM family member 8, RNF31 E3 ubiquitin-protein ligase RNF31, CNTNAP2 contactin-associated protein-like 2, SRP14 signal recognition particle 14 kDa protein.

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