Table 4 MIC and MBC values of the 5-butyl-2-pyridine carboxylic acid against pathogenic bacteria.

From: Production and characterization of a broad-spectrum antimicrobial 5-butyl-2-pyridine carboxylic acid from Aspergillus fumigatus nHF-01

Gram status

Bacteria

Concentration (mg/mL)

MIC

MBC

Gram-positive

B. cereus MTCC 1272

0.069 ± 0.0034

0.139 ± 0.006

B. subtilis MTCC 411

0.279 ± 0.012

0.557 ± 0.021

E. faecalis MCC 2041T

8.925 ± 0.41

17.85 ± 0.85

M. smegmatis mc2 155

4.46 ± 0.20

8.925 ± 0.379

S. aureus MTCC 96

0.557 ± 0.022

1.12 ± 0.052

S. epidermidis MTCC 3086

8.925 ± 0.39

17.85 ± 0.78

S. mutans MTCC 890

0.557 ± 0.025

1.12 ± 0.038

Gram-negative

E. coli MTCC 723

8.925 ± 0.40

17.85 ± 0.776

E. coli ATCC DH5α

4.46 ± 0.175

8.925 ± 0.354

K. pneumonia MTCC 7407

0.557 ± 0.021

1.12 ± 0.019

P. aeruginosa MTCC 741

0.557 ± 0.025

1.12 ± 0.023

S. enterica serovar Typhimurium MTCC 98

0.069 ± 0.0034

0.139 ± 0.0065

V. parahaemolyticus MTCC 451

1.12 ± 0.019

2.23 ± 0.10

  1. Here, the values are the average of triplicate trials ± SE, while the 'MIC' and 'MBC' indicate the values of the active compound that caused significant loss of viability of the organisms.
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