Figure 2
From: TLR4 and SARM1 modulate survival and chemoresistance in an HPV-positive cervical cancer cell line
TLR4KO and SARM1KO cells show reduced clonogenic and migration potentials. (a) Number of colonies formed by TLR4KO, SARM1KO and parental HeLa cells after 10 days of low-density seeding. 1000 cells of each cell line were seeded in 6-well plates and colony formation was assessed using crystal violet staining. (b) Percentage of wound healing by TLR4KO, SARM1KO and parental cells after 24 h and 48 h. (c) Representative micrographs of TLR4KO, SARM1KO and parental cells 24 and 48 h after the wound was performed. The wound healing assay was performed after mitomycin C treatment. Data in A and B displayed as mean ± SD. (**p ≤ 0.01; ****p ≤ 0.0001)
