Figure 2 | Scientific Reports

Figure 2

From: Adenosine inhibits TNFα-induced MMP-3 production in MH7A rheumatoid arthritis synoviocytes via A2A receptor signaling

Figure 2

Detection of functional A2A AdoR expression in MH7A cells. Adenosine A2A receptors in MH7A cells are functionally coupled to adenylyl cyclase and intracellular cAMP production. Cells were stimulated for 30 min with the indicated concentration of A2A AdoR agonist HENECA. Experiments were repeated three times, and data are presented as the mean ± SD. ★p < 0.01 versus 0 μM HENECA. Intracellular cAMP levels were measured using an enzyme immunoassay.

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