Table 1 Baseline characteristics of the study population.

From: Early menopause is associated with increased risk of retinal vascular occlusions: a nationwide cohort study

Variables

Total (N = 2,289,347)

1. Demographic factors

Age, years, mean ± SD

62.41 ± 8.25

Age group, No. (%)

 50–54 years

471,472 (20.59)

 55–59 years

496,721 (21.70)

 60–64 years

514,585 (22.48)

 65–69 years

291,718 (12.74)

 70–74 years

310,752 (13.57)

 75–79 years

125,953 (5.50)

 ≥ 80 years

78,146 (3.41)

Income, No. (%)

 Q1 (lowest)

520,295 (22.73)

 Q2

404,520 (17.67)

 Q3

540,526 (23.61)

 Q4 (highest)

824,006 (35.99)

2. Systemic comorbidities

Hypertension, No. (%)

 No

1,331,201 (58.15)

 Yes

958,146 (41.85)

Diabetes mellitus, No. (%)

 No

1,955,305 (85.41)

 Yes

334,042 (14.59)

Dyslipidemia, No. (%)

 No

1,624,088 (70.94)

 Yes

665,259 (29.06)

Stroke, No. (%)

 No

2,253,049 (98.41)

 Yes

36,298 (1.59)

Heart diseases, No. (%)

 No

2,196,562 (95.95)

 Yes

92,785 (4.05)

Chronic kidney disease, No. (%)

 No

2,100,209 (91.74)

 Yes

189,138 (8.26)

3. Behavioral factors

Smoking history, No. (%)

 Never smoked

2,210,674 (96.56)

 Former smoker

25,971 (1.13)

 Current smoker

52,702 (2.30)

Drinking habit, No. (%)

 None

1,987,784 (86.83)

 Mild

283,589 (12.39)

 Heavy

17,974 (0.79)

Regular physical activity, No. (%)

 No

1,796,638 (78.48)

 Yes

492,709 (21.52)

Body mass index, No (%)

 < 18.5 kg/m2

54,225 (2.37)

 18.5 to < 23 kg/m2

840,944 (36.73)

 23 to < 25 kg/m2

590,348 (25.79)

 25 to < 30 kg/m2

705,413 (30.81)

 ≥ 30 kg/m2

98,417 (4.30)

4. Reproductive factors

Age at menarche, mean ± SD

16.19 ± 2.02

Age at menarche in group, No. (%)

 < 14 years

142,577 (6.23)

 14–15 years

734,166 (32.07)

 16–17 years

875,342 (38.24)

 ≥ 18 years

537,262 (23.47)

Age at menopause, mean ± SD

50.63 ± 3.91

Age at menopause in group, No. (%)

 < 45 years

120,874 (5.28)

 45–49 years

529,786 (23.14)

 50–54 years

1,333,631 (58.25)

 ≥ 55 years

305,056 (13.33)

Parity, No. (%)

 Nulliparous

40,211 (1.76)

 1 child

186,256 (8.14)

 ≥ 2 children

2,062,880 (90.11)

Duration of breastfeeding, No. (%)

 Never

191,413 (8.36)

 < 0.5 year

208,816 (9.12)

 0.5 to < 1 year

426,428 (18.63)

 ≥ 1 year

1,462,690 (63.89)

Hormone replacement therapy, No. (%)

 Never used

1,834,474 (80.13)

 < 2 years

202,796 (8.86)

 2 to < 5 years

86,281 (3.77)

 ≥ 5 years

70,579 (3.08)

 Unknown

95,217 (4.16)

Oral contraceptive pill use, No. (%)

 Never used

1,838,861 (80.32)

 < 1 year

201,721 (8.81)

 ≥ 1 year

134,661 (5.88)

 Unknown

114,104 (4.98)

  1. SD, standard deviation; Q, quartile.