Figure 2
From: OCT1-target neural gene PFN2 promotes tumor growth in androgen receptor-negative prostate cancer
Analysis of OCT1 and putative OCT1-regulated gene expression in AR-negative CRPC. Representative images of immunohistochemistry for ACSL3 (A) and OCT1 (B) in PDX 201.2A-Cx. Scale bars equal 50 µm. (C) Line graph showing the number of putative super-enhancers defined by ranked AcH3K27 signal. (D) Top twenty highly expressed genes in the vicinity of OCT1-binding sites in PDX 201.2A-Cx. (E) Top twenty highly expressed genes among the putative super-enhancer associated genes in the vicinity of Oct1-binding sites in PDX 201.2A-Cx.
