Table 1 The demographics and characteristics of patients according to treatment received.
Variables | Total | Surgery only | SROC | SCRT | No surgery | P-value |
|---|---|---|---|---|---|---|
n = 1639 (%) | n = 282 (17.2%) | n = 534 (32.6%) | n = 525 (32.0%) | n = 298 (18.2%) | ||
Age groups, years, % | ||||||
≤ 40 years | 536 (32.7%) | 84 (15.7%) | 179 (33.4%) | 176 (32.8%) | 97 (18.1%) | 0.834 |
41–45 years | 509 (31.0%) | 88 (17.3%) | 169 (33.2%) | 165 (32.4%) | 87 (17.1%) | |
> 45 years | 594 (36.2%) | 110 (18.5%) | 186 (31.3%) | 184 (31.0%) | 114 (19.2%) | |
Sex, % | ||||||
Male | 924 (56.4%) | 140 (15.2%) | 279 (30.2%) | 309 (33.4%) | 196 (21.2%) | < 0.001 |
Female | 715 (43.6%) | 142 (19.9%) | 255 (35.7%) | 216 (30.2%) | 102 (14.3%) | |
Race, % | ||||||
White | 1084 (66.1%) | 187 (17.3%) | 336 (31.0%) | 343 (31.6%) | 218 (20.1%) | 0.104 |
Black | 218 (13.3%) | 38 (17.4%) | 73 (33.5%) | 77 (35.3%) | 30 (13.8%) | |
Othersa | 337 (20.6%) | 57 (16.9%) | 125 (37.1%) | 105 (31.2%) | 50 (14.8%) | |
Marital status, % | ||||||
Married | 993 (60.6%) | 158 (15.9%) | 339 (34.1%) | 326 (32.8%) | 170 (17.1%) | 0.280 |
Unmarried | 454 (27.7%) | 85 (18.7%) | 141 (31.1%) | 136 (30.0%) | 92 (20.3%) | |
Othersb | 192 (11.7%) | 39 (20.3%) | 54 (28.1%) | 63 (32.8%) | 36 (18.8%) | |
Location, % | ||||||
C16.0/C16.1 | 488 (29.8%) | 43 (8.8%) | 92 (18.9%) | 197 (40.4%) | 156 (32.0%) | < 0.001 |
C16.2 | 200 (12.2%) | 30 (15.0%) | 95 (47.5%) | 44 (22.0%) | 31 (15.5%) | |
C16.3/C16.4 | 436 (26.6%) | 99 (22.7%) | 151 (34.6%) | 156 (35.8%) | 30 (6.9%) | |
C16.5/C16.6 | 253 (15.4%) | 48 (19.0%) | 93 (36.8%) | 71 (28.1%) | 41 (16.2%) | |
C16.8/C16.9 | 262 (16.0%) | 62 (23.7%) | 103 (39.3%) | 57 (21.8%) | 40 (15.3%) | |
Tumor size, % | ||||||
≤ 3 cm | 554 (33.8%) | 160 (28.9%) | 164 (29.6%) | 155 (28.0%) | 75 (13.5%) | < 0.001 |
3.1–5.0 cm | 460 (28.0%) | 53 (11.5%) | 148 (32.2%) | 162 (35.2%) | 97 (21.1%) | |
> 5.0 cm | 625 (38.1%) | 69 (11.0%) | 222 (35.5%) | 208 (33.3%) | 126 (20.2%) | |
Grade, % | ||||||
I/II | 321 (19.6%) | 53 (16.5%) | 70 (21.8%) | 123 (38.3%) | 75 (23.4%) | < 0.001 |
III/IV | 1318 (80.4%) | 229 (17.4%) | 464 (35.2%) | 402 (30.5%) | 223 (16.9%) | |
Histological type, % | ||||||
Adenocarcinoma | 1050 (64.1%) | 162 (15.4%) | 321 (30.6%) | 349 (33.2%) | 218 (20.8%) | < 0.001 |
SRCC | 563 (34.4%) | 114 (20.2%) | 207 (36.8%) | 164 (29.1%) | 78 (13.9%) | |
Othersc | 26 (1.6%) | 6 (23.1%) | 6 (23.1%) | 12 (46.2%) | 2 (7.7%) | |
AJCC TNM stage, % | ||||||
I | 272 (16.6%) | 162 (59.6%) | 61 (22.4%) | 33 (12.1%) | 16 (5.9%) | < 0.001 |
II | 447 (27.3%) | 43 (9.6%) | 147 (32.9%) | 210 (47.0%) | 47 (10.5%) | |
III | 540 (32.9%) | 46 (8.5%) | 210 (38.9%) | 252 (46.7%) | 32 (5.9%) | |
IV | 380 (23.2%) | 31 (8.2%) | 116 (30.5%) | 30 (7.9%) | 203 (53.4%) | |
AJCC_T stage, % | ||||||
T1 | 300 (18.3%) | 148 (49.3%) | 42 (14.0%) | 34 (11.3%) | 76 (25.3%) | < 0.001 |
T2 | 172 (10.5%) | 28 (16.3%) | 65 (37.8%) | 59 (34.3%) | 20 (11.6%) | |
T3 | 626 (38.2%) | 44 (7.0%) | 196 (31.3%) | 282 (45.0%) | 104 (16.6%) | |
T4 | 541 (33.0%) | 62 (11.5%) | 231 (42.7%) | 150 (27.7%) | 98 (18.1%) | |
AJCC_N stage, % | ||||||
N0 | 529 (32.3%) | 187 (35.3%) | 128 (24.2%) | 110 (20.8%) | 104 (19.7%) | < 0.001 |
N1 | 433 (26.4%) | 22 (5.1%) | 133 (30.7%) | 137 (31.6%) | 141 (32.6%) | |
N2 | 303 (18.5%) | 26 (8.6%) | 109 (36.0%) | 136 (44.9%) | 32 (10.6%) | |
N3 | 374 (22.8%) | 47 (12.6%) | 164 (43.9%) | 142 (38.0%) | 21 (5.6%) | |
AJCC_M stage, % | ||||||
M0 | 1259 (76.8%) | 251 (19.9%) | 418 (33.2%) | 495 (39.3%) | 95 (7.5%) | < 0.001 |
M1 | 380 (23.2%) | 31 (8.2%) | 116 (30.5%) | 30 (7.9%) | 203 (53.4%) | |
Bone metastasis, % | ||||||
Yes | 42 (2.6%) | 1 (2.4%) | 6 (14.3%) | 1 (2.4%) | 34 (81.0%) | < 0.001 |
No/unknown | 1597 (97.4%) | 281 (17.6%) | 528 (33.1%) | 524 (32.8%) | 264 (16.5%) | |
Brain metastasis, % | ||||||
Yes | 6 (0.4%) | 0 (0.0%) | 1 (16.7%) | 1 (16.7%) | 4 (66.7%) | 0.021 |
No/unknown | 1633 (99.6%) | 282 (17.3%) | 533 (32.6%) | 524 (32.1%) | 294 (18.0%) | |
Liver metastasis, % | ||||||
Yes | 100 (6.1%) | 8 (8.0%) | 12 (12.0%) | 4 (4.0%) | 76 (76.0%) | < 0.001 |
No/unknown | 1539 (93.9%) | 274 (17.8%) | 522 (33.9%) | 521 (33.9%) | 222 (14.4%) | |
Lung metastasis, % | ||||||
Yes | 29 (1.8%) | 1 (3.4%) | 3 (10.3%) | 0 (0.0%) | 25 (86.2%) | < 0.001 |
No/unknown | 1610 (98.2%) | 281 (17.5%) | 531 (33.0%) | 525 (32.6%) | 273 (17.0%) | |