Figure 4
From: Temporal reproducibility of IgG and IgM autoantibodies in serum from healthy women
IgG (left) and IgM (right), by smoking status (never, former, current). IgG (a) and IgM (b) autoantibody profiling using HuProt arrays of repeat samples collected one year apart from n = 46 heathy subjects (n = 92 samples total). Raw log2 transformed data was used to cluster AAbs and samples using pearson distance higherarchical clustering for 18,303 IgG and 7,242 IgM AAbs with CV < 20%. Top bar annotation colors correspond to smoking status at blood donation (n = 7 current, 10 former, 29 never smokers). (Two samples from each subject clustered together for all 46 subjects, but did not cluster by smoking status).
