Figure 4
From: Vero cells gain renal tubule markers in low-calcium and magnesium chemically defined media
Enrichment map for significant downregulated GO-terms in biological processes for the comparison of Sus_CDM2 against Adh_CDM2 (threshold at FDR of 0.05). The size of the node is proportional to the number of identified genes annotated to the GO-term. The thickness of edges represents the level of overlap between the GO-terms. A: DNA templated transcription termination, B: Aerobic respiration, C: Response to increased oxygen levels, D: Protein peptidyl prolyl isomerization, E: Cofactor transport, F: positive regulation of inflammatory response, G: Cellular response to fluid shear stress, H: Regulation of ubiquitin protein ligase activity, I: Establishment of endothelial barrier, J: Hyperosmotic response, K: Regulation of protein oligomerization, L: Excitatory synapse assembly, M: Regulation of calcineurin mediated signaling, N: Modified amino acid transport, O: Cell migration involved in sprouting angiogenesis, P: Low density lipoprotein receptor particle metabolic process, Q: Endosome organization, R: Pyrimidine nucleotide triphosphate biosynthetic process, S: Water soluble vitamin metabolic process, T: Collagen catabolic process, U: Drug metabolic process. NES: Normalized enrichment score; The complete gene set list with group association is shown in Supplementary Table S8.
