Figure 7
In vivo biodistribution and localization of Au-NPs at different doses (High & Low) in rat kidney tissues. Confocal fluorescence images of rat kidney tissues (A) Control group, (B) Rat group treated with high dose Au-NPs, and (C) Rat group treated with low dose Au-NPs . (i) Blue: Hoechst 33342-stained nuclei. (ii) Red: Gold NPs. (iii) Merged Image from Gold NPs and Nuclei. (iv) DIC mode merged with Gold NPs (v) DIC mode merged with Gold NPs and nuclei. λmax = 505 nm (Hoechst 33342), 555 nm (red autofluorescence from gold NPs), 473 nm (Differential interference contrast [DIC]). (Confocal Laser Scanning Microscope × 63, Scale bar: 25 μm, Scan Mode = XYZ Unidirectional X, Scan Speed = 400 Hz, Pinhole Diameter = 137.1 μm).
