Figure 5 | Scientific Reports

Figure 5

From: Age and sex effects across the blood proteome after ionizing radiation exposure can bias biomarker screening and risk assessment

Figure 5

Pairwise comparison of fold change distribution for differentially abundant proteins unique for each age, sex and strain group. Proteins (dots) with differential abundance (|FC|≥ 3) in blood plasma 24 h after 0.5 Gy total body irradiation were associated with Gene Ontology terms; selected ionizing radiation-induced responses are shown, i.e. immune response (blue), cell cycle (yellow), and DNA damage and repair (red). Sex difference for each age group (A), age difference for each sex (B), and strain difference for each sex (juveniles, 7-weeks-old) (C). Note difference in scaling of y-axis. ♀, female; ♂, male. Please note that presented data is normalized to respective unirradiated control groups.

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