Figure 8 | Scientific Reports

Figure 8

From: Age and sex effects across the blood proteome after ionizing radiation exposure can bias biomarker screening and risk assessment

Figure 8The alternative text for this image may have been generated using AI.

Comparison of pooled and individual sample analysis. The overall correlation between pooled and individual analysis of blood plasma protein 24 h after 0.5 Gy total body irradiation is shown for female juvenile (7-weeks-old) black mice (A) and male juvenile (7-weeks-old) black mice (B). Note that the data are log-transformed and mean values for individual samples are shown. A representative protein-specific comparison of differential abundance obtained from pooled or individual analysis is shown for 15 randomly selected proteins with immune associated functions (C). Note that fold change (FC) is expressed in linear space. *Mean value; standard deviation (SD, parenthesis) for individual sample analysis is given as mean SD value for irradiated and control groups. Blue and orange indicate that relative abundance is higher or lower in pooled analysis than in individual analysis, respectively. Please note that presented data is normalized to respective unirradiated control groups.

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