Figure 5

Plasma levels of inflammatory markers in HICs and control groups. The graphs represent the concentrations measured by multiplex Luminex or ELISA assay of: (a) sVCAM-1; (b) sICAM-1; (c) AGP-1; (d) AGP-2; (e) D-dimer; (f) tPA; (g) TFPI; (h) ST2/IL-33R; Open circles on the X axis represent samples with undetectable levels of the marker; Colored horizontal bars represent the IQR and sample median, while gray boxplots represent linear model estimated adjusted means and 95% confidence intervals (CI 95%). Comparisons of means among groups were performed by contrasts/differences obtained after both bi- and multivariate-linear models fitted by ordinary least square regressions. p-values were corrected by the Tukey Honest Significant Difference post hoc method and represented as: *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001. Comparison graphs were plotted with Graphpad Prism v9.