Table 3 Hepatic oxidative (MDA) and antioxidative (GSH and SOD) parameters in EAC-bearing mice after treatment with amygdalin and/or sorafenib.

From: Amygdalin potentiates the anti-cancer effect of Sorafenib on Ehrlich ascites carcinoma and ameliorates the associated liver damage

Groups

MDA (nmol/g tissue)

GSH (nmol/g tissue)

SOD (U/g tissue)

Cnt

3.98 ± 0.11f

6.31 ± 0.16b

58.63 ± 1.23a

Amy

4.01 ± 0.14f

7.22 ± 0.23a

54.09 ± 1.99a

SorIP

4.08 ± 0.09f

6.06 ± 0.19b

55.28 ± 1.76a

SorOS

4.17 ± 0.17f

6.13 ± 0.18b

56.21 ± 2.38a

Amy + SorIP

4.12 ± 0.15f

5.98 ± 0.14b

54.14 ± 2.14a

Amy + SorOS

4.23 ± 0.16f

6.04 ± 0.15b

56.82 ± 1.77a

EAC

23.58 ± 0.76a

3.23 ± 0.11e

25.26 ± 0.54g

EAC + Amy

15.37 ± 0.43b

4.43 ± 0.13d

32.12 ± 0.77f

EAC + SorIP

10.50 ± 0.35d

5.14 ± 0.14c

39.32 ± 0.54d

EAC + SorOS

13.51 ± 0.32c

5.03 ± 0.15c

36.39 ± 0.42e

EAC + Amy + SorIP

7.30 ± 0.26e

6.35 ± 0.22b

47.05 ± 1.01b

EAC + Amy + SorOS

9.76 ± 0.36d

5.33 ± 0.16c

42.31 ± 0.63c

  1. Data were presented as means ± SEM. Small (a–g) letters showed the marked change at P ≤ 0.05. The significant were expressed by dissimilar letters in the same column.