Table 1 Comparisons of baseline characteristics according to diabetes presence in patients with acute coronary syndrome.

From: Interaction effects of diabetes and brain-derived neurotrophic factor on suicidal ideation in patients with acute coronary syndrome

 

Non-diabetes (N = 778)

Diabetes (N = 191)

Statistical coefficienta

P-value

Serum BDNF, mean (SD) ng/mL

18.0 (7.0)

17.1 (7.0)

t = 1.652

P = 0.099

BDNF Val66Met polymorphism, N (%) Met/Met

183 (23.5)

46 (24.1)

χ2 = 0.105

P = 0.949

Socio-demographic characteristics

Age, mean (SD) years

57.1 (11.2)

62.4 (9.6)

t = -6.526

P < 0.001

Sex, N (%) female

199 (25.6)

70 (36.6)

χ2 = 9.372

P = 0.002

Education, mean (SD) years

10.0 (4.6)

9.2 (4.7)

t = 2.029

P = 0.043

Marital status, N (%) unmarried

113 (14.5)

28 (14.7)

χ2 = 0.002

P = 0.962

Living alone, N (%)

70 (9.0)

22 (11.5)

χ2 = 1.134

P = 0.287

Housing, N (%) rented

129 (16.6)

21 (11.0)

χ2 = 3.658

P = 0.056

Currently unemployed, N (%)

277 (35.6)

91 (47.6)

χ2 = 9.438

P = 0.002

Laboratory assessment

Fasting glucose, mean (SD )mg/dL

125.9 (31.2)

174.7 (62.8)

t = -10.435

P < 0.001

Total cholesterol, mean (SD) mg/dL

187.1 (38.8)

178.6 (41.5)

t = 2.672

P = 0.008

BUN, mean (SD) mg/dL

14.8 (9.5)

17.3 (10.2)

t = − 3.106

P = 0.002

Creatinine, mean (SD) mg/dL

0.87 (0.27)

0.93 (0.35)

t = − 1.958

P = 0.051

Depression characteristics

Previous depression, N (%)

25 (3.2)

9 (4.7)

χ2 = 1.107

P = 0.313

Family history of depression, N (%)

18 (2.3)

5 (2.6)

χ2 = 0.061

P = 0.805

BDI, mean (SD) score

9.6 (8.5)

11.5 (9.0)

t = − 2.746

P = 0.006

Cardiac risk factors, N (%)

Previous ACS

31 (4.0)

8 (4.2)

χ2 = 0.017

P = 0.898

Family history of ACS

24 (3.1)

7 (3.7)

χ2 = 0.167

P = 0.683

Hypertension

338 (43.4)

120 (62.8)

χ2 = 23.114

P < 0.001

Hypercholesterolemia

403 (51.8)

83 (43.5)

χ2 = 4.271

P = 0.039

Obesity

336 (43.2)

79 (41.4)

χ2 = 0.209

P = 0.648

Current smoker

319 (41.0)

47 (24.6)

χ2 = 17.538

P < 0.001

Current cardiac status

Killip class > 1, N (%)

129 (16.6)

39 (23.2)

χ2 = 1.576

P = 0.209

LVEF, mean (SD)

61.8 (10.8)

58.6 (12.7)

t = 3.237

P = 0.001

Troponin I, mean (SD) mg/dL

9.9 (15.1)

10.0 (14.2)

t = − 0.127

P = 0.899

CK-MB, mean (SD) mg/dL

17.6 (37.8)

16.4 (35.1)

t = 0.413

P = 0.680

  1. aIndependent two-sample t-test or χ2 test, as appropriate. BDNF, brain-derived neurotrophic factor; BUN, blood urea nitrogen; BDI, Beck Depression Inventory; ACS, acute coronary syndrome; LVEF, left ventricular ejection fraction; CK-MB, creatine kinase-MB. Diabetes was defined as a diagnosis of diabetes by a doctor or currently administering antidiabetic drugs.
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