Figure 3
From: Protein-bound sialic acid in saliva contributes directly to salivary anti-influenza virus activity
Contribution of protein-bound sialic acid to salivary anti-IAV activity. Effect of α(2-3,6)-sialidase or heat treatment on (A) the concentration of BSA and (B) salivary anti-IAV activity against the PR8 IAV strain. (C) Hemagglutination inhibition assay with saliva (n = 8, A–H). The bar graph shows the HI titers of each subject. This experiment was repeated three times with similar results. (D) Correlation between salivary anti-IAV activity against the PR8 IAV strain and the HI titer of saliva. The plot shows a moderately positive correlation. (E) The effect of α(2-3,6)-sialidase and heat treatment on the HAI titer of saliva. Data are presented as mean ± SD for each group. Average plateau values were compared using one-way analysis of variance and Tukey’s test. ρ Spearman's correlation coefficient. *p < 0.05; ***p < 0.001.
