Table 1 Characteristics of women with uterine fibroid and the control group from the HIRA claim data.
From: Uterine fibroids increase the risk of thyroid goiter and thyroid nodules
Control | Uterine fibroid | Total | P value | Standardized difference | |
|---|---|---|---|---|---|
Number of participants | 181,419 | 181,419 | 362,838 | ||
Median age (years) | 40 [35–45] | 40 [35–44] | 40 [35–44] | < 0.001 | − 0.033 |
Age at inclusion (years) | < 0.001 | 0.109 | |||
20–24 | 2016 (1.1) | 2004 (1.1) | 4020 (1.1) | ||
25–29 | 12,456 (6.9) | 12,440 (6.9) | 24,896 (6.9) | ||
30–34 | 30,841 (17) | 30,775 (17) | 61,616 (17) | ||
35–39 | 39,134 (21.6) | 42,535 (23.4) | 81,669 (22.5) | ||
40–44 | 48,270 (26.6) | 52,926 (29.2) | 101,196 (27.9) | ||
45–49 | 48,702 (26.8) | 40,739 (22.5) | 89,441 (24.7) | ||
SES | 0.708 | − 0.001 | |||
Mid ~ high SES | 179,497 (98.9) | 179,520 (99) | 359,017 (98.9) | ||
Low SES | 1922 (1.1) | 1899 (1) | 3821 (1.1) | ||
Region | < 0.001 | − 0.097 | |||
Urban area | 103,771 (57.2) | 112,361 (61.9) | 216,132 (59.6) | ||
Rural area | 77,648 (42.8) | 69,058 (38.1) | 146,706 (40.4) | ||
CCI | 0.400 | 0.011 | |||
0 | 145,277 (80.1) | 145,741 (80.3) | 291,018 (80.2) | ||
1 | 23,150 (12.8) | 22,518 (12.4) | 45,668 (12.6) | ||
≥ 2 | 12,992 (7.2) | 13,160 (7.3) | 26,152 (7.2) | ||
Parity in cohort | 0.097 | 0.009 | |||
0 | 161,834 (89.2) | 162,263 (89.4) | 324,097 (89.3) | ||
1 | 12,763 (7) | 12,350 (6.8) | 25,113 (6.9) | ||
≥ 2 | 6822 (3.8) | 6806 (3.8) | 13,628 (3.8) | ||
Menopause | < 0.001 | − 0.130 | |||
No | 178,441 (98.4) | 178,738 (98.5) | 357,179 (98.4) | ||
Yes | 2978 (1.6) | 2681 (1.5) | 5659 (1.6) | ||
Hypertension | < 0.001 | ||||
No | 169,400 (93.4) | 170,607 (94) | 340,007 (93.7) | ||
Yes | 12,019 (6.6) | 10,812 (6) | 22,831 (6.3) | ||
DM | < 0.001 | ||||
No | 172,727 (95.2) | 174,169 (96) | 346,896 (95.6) | ||
Yes | 8692 (4.8) | 7250 (4) | 15,942 (4.4) | ||
Dyslipidemia | < 0.001 | ||||
No | 156,805 (86.4) | 157,623 (86.9) | 314,428 (86.7) | ||
Yes | 24,614 (13.6) | 23,796 (13.1) | 48,410 (13.3) | ||
SLE | < 0.001 | ||||
No | 181,049 (99.8) | 181,180 (99.9) | 362,229 (99.8) | ||
Yes | 370 (0.2) | 239 (0.1) | 609 (0.2) | ||
IBD | < 0.001 | ||||
No | 158,459 (87.3) | 161,086 (88.8) | 319,545 (88.1) | ||
Yes | 22,960 (12.7) | 20,333 (11.2) | 43,293 (11.9) | ||
Crohn's disease | < 0.001 | ||||
No | 181,333 (100) | 181,383 (100) | 362,716 (100) | ||
Yes | 86 (0) | 36 (0) | 122 (0) | ||
Endometriosis | < 0.001 | ||||
No | 177,511 (97.8) | 158,076 (87.1) | 335,587 (92.5) | ||
Yes | 3908 (2.2) | 23,343 (12.9) | 27,251 (7.5) | ||
