Figure 2 | Scientific Reports

Figure 2

From: Bone marrow transplantation induces changes in the gut microbiota that chronically increase the cytokine response pattern of splenocytes

Figure 2

The effect of co-housing after BMT on cytokine secretion of stimulated peritoneal macrophages. Spiderplots show IL-6 and TNF-α release in response to various pathogenic stimuli from peritoneal macrophages derived from (a) BMT-treated mice co-housed with BMT mice (outer light blue lines), (b) BMT-treated mice co-housed with healthy control mice (outer dark blue lines), and (c) control co-housed mice co-housed with BMT-treated mice (outer red lines). Cytokine concentrations in response to the stimuli are normalized to the cytokine concentrations of healthy control mice co-housed with control mice (inner grey lines), averaged per group and plotted on a log scale. See legend to Fig. 1 for more information. Groups were compared using Mann–Whitney U test; n = 6; *p < 0.05.

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