Figure 1
miR-601 is downregulated in OS and related to poor outcome. (a) A histogram showed the 16 most downregulated miRNAs in OS cells compared with normal osteocytes. (b) The histogram showed the miR-601 expression in OS cells compared with normal osteocytes. (c) The miR-601 expression was evaluated by RT-qPCR assay in 5 OS cell lines and normal bone cells. (d, e) The expression of miR-601 was evaluated by RT-qPCR assay in 66 paired OS tissues and normal tissues (NB). (f) Kaplan–Meier curves analysis showed overall survival of 66 OS patients in miR-601 high and low groups. Patients were divided into "high" and "low" group with the 50th percentile expression of miR-601 as the critical point.
