Table 1 Distribution of the clinical characteristics at baseline by quartiles of CA15-3.

N

539

129

131

130

130

Age, years

59.57 ± 16.36

50.17 ± 14.66

59.12 ± 16.36

61.26 ± 15.46

68.64 ± 13.27

< 0.001

Male

296 (54.9)

52 (40.3)

71 (54.2)

76 (58.5)

86 (66.2)

< 0.001

History

Respiratory disease

88 (16.3)

12 (9.3)

15 (11.5)

25 (19.2)

35 (26.9)

< 0.001

Smoking

0.016

No

394 (74.9)

101 (79.5)

99 (78.6)

99 (78.0)

81 (63.8)

Yes

30 (5.7)

5 (3.9)

10 (7.9)

4 (3.1)

9 (7.1)

Former

102 (19.4)

21 (16.5)

17 (13.5)

24 (18.9)

37 (29.1)

Hypertension

237 (44.0)

32 (24.8)

60 (45.8)

67 (51.5)

71 (54.6)

< 0.001

Diabetes

140 (26.0)

29 (22.5)

29 (22.1)

36 (27.7)

38 (29.2)

0.443

Cardiovascular disease

92 (17.1)

9 (7.0)

19 (14.5)

22 (16.9)

38 (29.2)

< 0.001

History of cancer

46 (8.6)

4 (3.1)

6 (4.6)

10 (7.7)

23 (17.8)

< 0.001

Characteristics at admission

Length of symptoms, days

6 [3, 9]

6 [3, 8]

6 [3, 8]

6 [3, 9.25]

6 [3, 10]

0.569

Facility of admission

0.001

Ward

499 (92.6)

126 (97.7)

123 (93.9)

121 (93.1)

110 (84.6)

Intensive care

40 (7.4)

3 (2.3)

8 (6.1)

9 (6.9)

20 (15.4)

WHO scale

3.73 ± 0.63

3.57 ± 0.54

3.72 ± 0.62

3.78 ± 0.65

3.89 ± 0.68

< 0.001

D-dimer, ng/mL

272 [177, 511]

216 [150, 318]

261 [167, 528]

301 [197, 517]

334 [224, 817]

< 0.001

Ferritine, ng/mL

457 [227, 993]

366 [158, 690]

474 [232, 970]

501 [245, 1008]

691 [292, 1411]

< 0.001

IL-6, pg/mL

38.4 [15.2, 69.3]

28.1 [12.5, 55.8]

39.2 [13.1, 70.8]

41.7 [17.9, 69.2]

43 [21.4, 82.2]

0.008

CRP, mg/dL

6.09 [2.62, 11.6]

4.24 [1.83, 9.05]

7.28 [3.04, 13.18]

6.34 [2.8, 11.4]

6.54 [3.29, 12.9]

0.011

TnT-hs, pg/mL

8 [5, 16]

5 [3.62, 7]

7.03 [5, 12.8]

9 [6, 18.8]

15 [8, 26.8]

< 0.001

NT-proBNP, pg/mL

124 [40, 405]

67 [24.1, 164]

100 [35.9, 279]

154 [54.7, 342]

270 [80.8, 1197]

< 0.001