Table 3 Multivariable adjusted analysis of predictors at baseline of complications during in-hospital evolution of patients with COVID19.

From: CA 15-3 prognostic biomarker in SARS-CoV-2 pneumonia

 

Death

Intensive care

O2 at discharge

OR (95% CI)

p

OR (95% CI)

p

OR (95% CI)

p

Age, per 10 years

1.49 (1.01, 2.27)

0.053

0.85 (0.59, 1.24)

0.396

1.21 (0.85, 1.76)

0.298

Male

1.30 (0.49, 3.58)

0.599

2.15 (0.86, 5.67)

0.108

4.61 (1.79, 13.0)

0.002

Respiratory disease

1.56 (0.58, 4.07)

0.365

1.14 (0.42, 2.98)

0.787

2.30 (0.94, 5.56)

0.065

Smoking history

0.52 (0.17, 1.45)

0.224

0.65 (0.24, 1.65)

0.378

0.74 (0.28, 1.86)

0.526

Hypertension

0.91 (0.36, 2.36)

0.845

0.93 (0.37, 2.30)

0.877

0.74 (0.31, 1.72)

0.486

Diabetes

0.70 (0.28, 1.67)

0.433

0.48 (0.17, 1.26)

0.153

0.70 (0.28, 1.64)

0.420

Cardiovascular disease

0.48 (0.17, 1.29)

0.156

0.27 (0.07, 0.93)

0.048

0.96 (0.34, 2.58)

0.937

History of cancer

2.54 (0.90, 7.01)

0.073

1.88 (0.55, 6.07)

0.299

0.78 (0.17, 3.06)

0.734

WHO scale, per unit

4.21 (2.14, 8.92)

< 0.001

63.1 (22.1, 227)

< 0.001

33.1 (11.4, 126)

< 0.001

D-dimer, log10

1.97 (0.86, 4.38)

0.098

0.86 (0.30, 2.42)

0.780

0.85 (0.31, 2.18)

0.740

Ferritin, log10

2.31 (0.91, 6.20)

0.086

4.57 (1.64, 13.7)

0.005

1.49 (0.56, 3.97)

0.426

IL-6, log10

2.17 (0.93, 5.43)

0.083

1.50 (0.64, 3.79)

0.367

1.82 (0.67, 5.45)

0.258

CRP, log10

0.55 (0.17, 1.80)

0.312

0.43 (0.13, 1.37)

0.153

1.53 (0.49, 4.91)

0.465

TnThs, log10

10.2 (2.48, 44.4)

0.001

2.41 (0.58, 9.94)

0.220

5.10 (1.22, 21.2)

0.024

NT-proBNP, log10

1.06 (0.54, 2.04)

0.871

1.34 (0.66, 2.72)

0.419

1.27 (0.67, 2.44)

0.461

CA15-3

0–16.7, reference

–

–

–

–

–

–

16.7–34.5

1.38 (0.52, 3.86)

0.523

1.01 (0.41, 2.49)

0.977

0.54 (0.24, 1.19)

0.130

> 34.5

3.74 (1.22, 11.9)

0.022

4.56 (1.37, 15.8)

0.014

0.75 (0.19, 2.70)

0.666

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