Figure 3
From: Neuropsychiatric symptoms and seizure related with serum cytokine in epilepsy patients

Seizure frequency, disease duration, and the number of AEDs and cytokines. We compared seizure frequency, disease duration, and the number of AEDs of lower (Q1) and upper quartile (Q4) of IL-1β, IL-2, IL-6, IFN-γ, CCL2, and CCL5. There was no significant difference in seizure frequency between Q1 and Q4 of IL-1β, IL-2, IL-6, IFN-γ, and CCL5, except on CCL2, seizure frequency was lower in Q4 (p-value = 0.039). The disease duration was longer in Q4 of IL-6 (p-value = 0.018). There was no significant difference of AED numbers between Q1 and Q4.