Figure 7
Volcano plot of the in silico data validation performed using glomerular gene expression data from Nephroseq and glomerular mRNA sequencing data from Levin et al.28. Human gene names are reported in uppercase, mouse genes names in lowercase. (a) Hodgin et al.34 db/db C57BLKS mouse model—DKD vs non-DKD. (b) Hodgin et al., eNOS-deficient C57BLKS db/db mouse model—DKD vs non-DKD. (c) Hodgin et al., DBA/2 mouse model—DKD vs non-DKD. (d) Ju et al.35 DKD human renal biopsies vs healthy individuals. (e) Levin et al.28 DKD human renal biopsies vs healthy individuals. (f) Woroniecka et al.36 DKD human renal biopsies vs healthy individuals. For the outliers, the relative percentiles were reported after the gene names and. COPA values were plotted instead of log2 fold changes.
