Figure 1 | Scientific Reports

Figure 1

From: Purine nucleoside phosphorylase deficiency induces p53-mediated intrinsic apoptosis in human induced pluripotent stem cell-derived neurons

Figure 1

Reduced soma and nuclei volume in PNP-deficient induced pluripotent stem cell-derived neurons. (A) Representative immunofluorescence microscopy images depicting the soma and nuclei of neurons derived from control (CTL) and PNP-deficient (PNP−/−) iPSCs. The average soma (B) and nuclei (C) volumes of CTL and PNP−/− neurons. Data are the mean + SD of n = 1050 (350 neurons from 3 replicates); * p < 0.001.

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