Figure 11

Neutralization of edema inducing activity of GIIA by elemolic acid. GIIA (5 µg) was pre-incubated with indicated concentration of elemolic acid (3 to 18 µM) for 30 min and injected into the right footpad of the hind limb of mice and the respective left footpad received vehicle (saline). After 45 min, mice were euthanized, and their legs were removed at the ankle joints and weighed separately. The edema ratio was calculated. The data are expressed in mean ± standard deviation (n = 3).