Table 1 Number of mice used per experiment.
Experiment | WT | Ctsk−/− | |
|---|---|---|---|
Figure 1A | Formalin Injection—Nocifensive behavior | 8 | 8 |
Figure 1B | Locomotor activity | 5 | 4 |
Figure 1C,D | Mechanical Hypersensitivity (Traditional Method) | 8 | 9 |
Figure 1E,F | Thermal Hypersensitivity | 28 | 24 |
Figure 2B | Dose Response curve (Cathepsin K inhibitor) | 54 | |
Figure 3 | Mechanical Hypersensitivity following Cathepsin K inhibitor treatment | 72 | |
Figure 4 | Thermal Hypersensitivity following Cathespin K inhibitor treatment | 17 | |
Figure 5A | mRNA expression following CFA injection | 31 | |
Figure 5B | Cathepsin K activity following CFA injection | 31 | |
Total mice | 254 | 45 |
