Figure 3

Behavioral effects of prenatal stress in juvenile mice. Locomotion was assessed in the open field test (a,b), while spontaneous alternation was evaluated in the Y maze (c,d). Social interaction was measured during a 3-min encounter with an adult NMRI WT female (e,f). *p < 0.05; * in grey p = 0.06; #p < 0.05 versus chance level (indicated by dotted line). N for males: 14 (a,e) or 13 (c) WT-no stress, 9 (a,c,e) WT-stress, 8 (a,e) or 9 (c) KO-no stress, 11 (a,e) or 10 (c) KO-stress; N for females: 12 in all groups (b,d,f). KO refers to -/Y in males, HET to +/− in females. Data are expressed as mean ± SEM.