Table 1 Clinical characteristics of subjects (n = 347) at baseline and 12-month examinations.

From: Possible role of insulin resistance in activation of plasma xanthine oxidoreductase in health check-up examinees

 

Baseline

12-month

Age, years

47.0 (41.0–53.0)

 

Males, n

173 (49.9)

 

Alcohol drinking habit, n

145 (41.8)

151 (43.5)

Smoking habit, n

55 (15.9)

52 (15.0)

BMI, kg/m2

22.5 (20.5–24.5)

22.7 (20.6–24.8)

Waist circumference, cm

81.5 (76.4–87.5)

82.5 (76.4–88.5)

AST, U/L

19.0 (16.0–23.0)

19.0 (16.0–23.0)

ALT, U/L

17.0 (12.0–23.0)

16.0 (13.0–23.0)

eGFR, mL/min/1.73 m2

80.9 (72.5–89.9)

78.6 (70.9–85.8)

FPG, mg/dL

99.0 (94.0–105.0)

99.0 (94.0–105.0)

HbA1c, %

5.6 (5.4–5.8)

5.6 (5.4–5.8)

Uric acid, mg/dL

5.2 (4.3–6.1)

5.2 (4.3–6.1)

HOMA-IR

1.2 (0.9–1.7)

1.1 (0.8–1.7)

Plasma XOR activity, pmol/h/mL

32.1 (19.8–56.0)

33.0 (20.5–54.5)

  1. Values are expressed as median (interquartile range) or number (%).
  2. BMI body mass index, AST aspartate aminotransferase, ALT alanine aminotransferase, eGFR estimated glomerular filtration rate, FPG fasting plasma glucose, HbA1c glycated hemoglobin, HOMA-IR homeostatic model assessment of insulin resistance, XOR xanthine oxidoreductase.