Table 2 Comparison of clinical characteristics between subjects with and without IR at baseline.

From: Possible role of insulin resistance in activation of plasma xanthine oxidoreductase in health check-up examinees

 

With IR

(n = 92)

Without IR

(n = 255)

p

Age, years

48.0 (42.0–54.0)

46.0 (41.0–53.0)

0.406

Males, n

47 (51.1)

126 (49.4)

0.783

Alcohol drinking habit, n

38 (41.3)

107 (42.0)

0.913

Smoking habit, n

15 (16.3)

40 (15.7)

0.889

BMI, kg/m2

25.0 (23.2–27.0)

21.6 (20.0–23.4)

 < 0.001

Waist circumference, cm

87.8 (82.1–94.0)

79.1 (74.0–84.5)

 < 0.001

AST, U/L

20.0 (17.0–23.8)

19.0 (16.0–23.0)

0.101

ALT, U/L

22.0 (16.0–32.8)

16.0 (11.0–20.0)

 < 0.001

eGFR, mL/min/1.73 m2

82.5 (72.8–91.4)

79.7 (72.4–89.6)

0.342

FPG, mg/dL

104.0 (99.0–109.0)

96.0 (93.0–103.0)

 < 0.001

HbA1c, %

5.7 (5.5–5.9)

5.6 (5.4–5.7)

 < 0.001

Uric acid, mg/dL

5.5 (4.5–6.5)

4.8 (4.0–5.9)

0.002

HOMA-IR

2.3 (2.0–2.8)

1.0 (0.7–1.3)

 < 0.001

Plasma XOR activity, pmol/h/mL

47.6 (30.1–95.0)

27.4 (17.7–48.7)

 < 0.001

  1. Values are expressed as median (interquartile range) or number (%). p Values are shown for comparisons between subjects with (HOMA-IR ≥ 1.7) and without (HOMA-IR < 1.7) IR.
  2. IR insulin resistance, BMI body mass index, AST aspartate aminotransferase, ALT alanine aminotransferase, eGFR estimated glomerular filtration rate, FPG fasting plasma glucose, HbA1c glycated hemoglobin, HOMA-IR homeostatic model assessment of insulin resistance, XOR xanthine oxidoreductase.
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