Table 3 Comorbidities as risk factors for hospitalization.

From: Course of disease and risk factors for hospitalization in outpatients with a SARS-CoV-2 infection

Risk factor

Individuals with this risk factor*

Univariate analyses

Multivariate analyses***

OR (95% CI)

p-value

OR (95% CI)

p-value

Age ≥ 60

329 (39.5%)

5.66 (3.93–8.15)

 < 10–20

3.52 (2.02–6.20)

1.3 × 10–5

Male sex

365 (43.6%)

2.31 (1.65–3.24)

8.0 × 10–7

  

Cardiovascular diseases

132 (15.9%)

4.70 (3.16–6.99)

6.5 × 10–16

1.84 (1.05–3.23)

0.03

Hypertension

345 (41.4%)

2.47 (1.75–3.46)

1.3 × 10–7

  

Peripheral artery disease

17 (2.0%)

4.47 (1.70–11.8)

0.001

  

Diabetes mellitus

94 (11.3%)

4.54 (2.90–7.10)

1.6 × 10–12

2.41 (1.32–4.39)

0.004

Pulmonary disease

97 (11.6%)

2.68 (1.71–4.20)

1.0 × 10–5

  

COPD

20 (2.4%)

23.1 (6.69–79.7)

1.8 × 10–12

5.95 (1.36–26.2)

0.02

Asthma

38 (4.5%)

0.55 (0.21–1.43)

ns

  

Neurological disease

88 (10.6%)

5.81 (3.66–9.21)

4.5 × 10–16

3.22 (1.70–6.09)

3.4 × 10–4

Stroke

27 (3.3%)

6.16 (2.80–13.54)

3.5 × 10–7

  

Neurological disease and stroke

69 (8.3%)

5.49 (3.30–9.14)

8.7 × 10–13

  

Neurological disease other than stroke

61 (7.2%)

4.71 (2.76–8.04)

9.2 × 10–10

  

Kidney diseases

59 (7.1%)

5.00 (2.90–8.59)

3.1 × 10–10

2.48 (1.19–5.15)

0.02

Disability**

137 (19.7%)

3.56 (1.79–7.07)

1.3 × 10–4

  

ACE or AT1 inhibitors

264 (50.5%)

2.23 (1.46–3.41)

1.8 × 10–4

  

ACE inhibitors

133 (25.4%)

1.78 (1.14–2.78)

0.01

  

AT1 antagonists

133 (25.4%)

1.53 (0.97–2.39)

ns

  
  1. ns not significant.
  2. *Percentages were calculated based on those individuals that answered the question.
  3. **Disability of any kind was documented only in the COVER study, not the ViP study.
  4. ***Multivariate analyses were performed using binary logistic regression with forward inclusion.