Figure 8

EMI-based multicellular simulations of electrical propagation and re-entry in the cylinder segment of the PV sleeve tissue. We use the simulation protocol described in the “Re-entry” section for investigating re-entry. Data are illustrated for WT, and the N588K, A545P, and E299V mutations (columns). Specifically, we show the intracellular potential of the cells in the PV sleeve at five different times after stimulation (rows). Note that to improve the visual resolution, the transversal axis of the myocytes has again been stretched by a factor of 20.