Figure 1

Conserved and unique miRNAs in different patient populations. (a) The number of individual and shared miRNAs was determined in healthy controls (H) and HO patients with proven (HO-proven), probable (HO-probable) and possible (HO-possible) IA. (b) Normalized distribution patterns of the 190 conserved miRNAs in the H, HO-possible and HO-proven/probable groups are shown as circo plots, where red, orange and blue correspond to miRNAs with high (RPM > log104), medium (log102 < RPM < log104) and low (log101 < RPM < log102) read per million values, respectively. In every case the order of the miRNAs (the representative bars) was the same. Bar lengths refer to the log10 RPM sequence number.