Figure 2 | Scientific Reports

Figure 2

From: Circulating microRNA sequencing revealed miRNome patterns in hematology and oncology patients aiding the prognosis of invasive aspergillosis

Figure 2

Results of differential expression analysis of the 190 conserved miRNAs by comparing HO patients with (HO-proven, HO-probable) or without (HO-possible) IA. Volcano plot represents the DEMs showing statistically significant overexpression and underexpression (according to the log2-transformed fold change in relation to the -log10-transformed P-value). The dashed line on the y-axis indicates the P-value = 0.05 threshold with statistically significant (P < 0.05) gene expression (up- and downregulation, respectively). Red circles indicate DEMs. Highlighted DEMs represent IA-specific miRNAs whose gene expression was not influenced by hematological malignancies.

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