Figure 6 | Scientific Reports

Figure 6

From: Circulating microRNA sequencing revealed miRNome patterns in hematology and oncology patients aiding the prognosis of invasive aspergillosis

Figure 6

ROC curves were constructed to assess and visualize the performance of 8 preselected miRNAs. To measure the diagnostic accuracy of the miRNAs, relative fold changes were converted to qualitative (proven IA, probable IA vs. possible IA) indexes. The normalized CT values of eight miRNAs revealed their significant downregulation in IA-infected hematology and oncology patients (proven/probable) relative to noninfected patients (possible), indicating IA. Line graphs were used to calculate the optimal cutoff points. Scatter graphs represent the distribution of the CT values in cases and controls, and area plots represent the discriminatory power of the biomarkers.

Back to article page