Figure 2 | Scientific Reports

Figure 2

From: Whole genome sequencing of multidrug-resistant Mycobacterium tuberculosis isolates collected in the Czech Republic, 2005–2020

Figure 2

Maximum likelihood phylogenetic tree generated from 64 MDR isolates collected in the Czech Republic during the years 2005–2020 together with their lineage, cluster assignment, and genotypic resistance to first- and second-line antituberculosis drugs. The tree was annotated using iTOL v6 (https://itol.embl.de/). The first column denotes the lineages. The next 5 columns show genomic relatedness within clusters (CL12, CL5, CL2 and CL0—sets the maximum number of SNPs that differ from the genetically closest isolate). Mutations encoded resistance are represented by filled circles (presence of mutation) or empty circles (absence of mutation) icons. MDR multi-drug resistant, XDR extensively-drug resistant, drug-resistant (including mono- and poly-resistant).

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