Table 3 NPSI subscores and response rates in patients with spinal cord-related pain, radicular pain, and cauda equina syndrome.

From: Symptom-based pharmacotherapy for neuropathic pain related to spinal disorders: results from a patient-based assessment

 

Spinal cord-related pain

Radicular pain

Cauda equina syndrome

p

Number of patients

87

96

82

 

NPSI subscore

Superficial pain

31.0 ± 27.2‡

46.9 ± 31.0

35.7 ± 21.3

0.035*

Deep pain

25.7 ± 22.0‡

42.9 ± 27.9

36.3 ± 24.7

0.024*

Paroxysmal pain

37.4 ± 30.0

38.9 ± 23.8

32.2 ± 26.8

0.74

Evoked pain

15.8 ± 17.8†

40.0 ± 25.9

35.0 ± 22.2

< 0.01*

Paresthesia/dysesthesia

21.0 ± 20.9†

41.6 ± 23.9

35.8 ± 24.5

< 0.01*

Total pain reduction rate

25.2 ± 22.0‡

42.2 ± 26.0

33.6 ± 20.0

< 0.01*

Responder

30% Responder

36/87 (41.4)‡

66/96 (68.8)

52/82 (63.4)

< 0.01*

50% Responder

14/87 (16.1)‡

34/96 (35.4)

31/82 (37.8)

< 0.01*

  1. Data are shown as mean ± SD.
  2. NPSI Neuropathic Pain Symptom Inventory.
  3. *Significant differences among groups.
  4. †p<0.05, compared to patients with radicular pain and cauda equina syndrome.
  5. ‡p<0.05, compared to patients with radicular pain.
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