Table 5 The response rate of each drug for patients with an NPSI subscore ≥ 1.
Pregabalin | Mirogabalin | Duloxetine | Neurotropin | p | |
|---|---|---|---|---|---|
Superficial pain | |||||
Baseline NPSI subscore | 5.2±2.5 | 5.4±2.8 | 5.9±2.6 | 4.2±1.7 | 0.11 |
Follow-up NPSI subscore | 3.1±2.3 | 3.6±2.7 | 4.0±2.6 | 2.5±1.6 | 0.27 |
Response rate (%) | 40.4±30.3 | 38.8±26.7 | 34.9±26.3 | 43.7±24.0 | 0.74 |
Deep pain | |||||
Baseline NPSI subscore | 6.6±2.2 | 5.5±2.0 | 6.6±2.3 | 6.1±1.5 | 0.41 |
Follow-up NPSI subscore | 4.0±2.6 | 3.3±1.7 | 4.4±2.6 | 3.9±1.6 | 0.66 |
Response rate (%) | 40.9±32.0 | 39.3±23.2 | 35.1±29.3 | 38.1±13.0 | 0.93 |
Paroxysmal pain | |||||
Baseline NPSI subscore | 4.3±2.3 | 4.5±2.5 | 4.0±2.3 | 3.8±2.1 | 0.75 |
Follow-up NPSI subscore | 2.9±1.9 | 3.3±2.6 | 2.8±2.0 | 2.5±1.9 | 0.83 |
Response rate (%) | 34.2±29.1 | 33.8±26.6 | 35.2±28.4 | 40.0±17.5 | 0.86 |
Evoked pain | |||||
Baseline NPSI subscore | 3.7±2.7 | 4.9±2.5 | 4.1±2.9 | 3.9±2.2 | 0.41 |
Follow-up NPSI subscore | 2.7±2.4 | 3.6±2.5 | 3.2±2.6 | 2.6±2.1 | 0.44 |
Response rate (%) | 32.0±27.1 | 31.5±25.5 | 25.1±22.6 | 38.8±20.8 | 0.40 |
Paresthesia/dysesthesia | |||||
Baseline NPSI subscore | 5.0±2.4 | 4.9±2.0 | 5.5±2.6 | 4.6±2.0 | 0.67 |
Follow-up NPSI subscore | 3.5±2.3 | 3.4±2.1 | 4.0±2.4 | 2.7±1.8 | 0.10 |
Response rate (%) | 32.0±27.4 | 32.5±28.2 | 26.1±25.0 | 45.7±19.3 | 0.013* |
Total | |||||
Baseline NPSI score | 15.0±10.0 | 15.6±9.6 | 16.5±9.6 | 13.8±8.3 | 0.63 |
Follow-up NPSI score | 10.1±8.2 | 10.5±7.6 | 11.7±8.0 | 8.5±6.4 | 0.29 |
Response rate (%) | 33.9±27.1 | 34.6±21.7 | 30.7±24.8 | 42.3±18.8 | 0.091 |
