Table 1 Comparison of baseline clinicodemographic characteristics of the groups.
Characteristic | Prednisolone alone group; n = 22 | Prednisolone + methotrexate group; n = 22 | p-value |
|---|---|---|---|
Age (years); mean ± SD | 40.86 ± 15.69 | 43 ± 11.61 | 0.61 |
Sex (M:F) | 13:9 | 8:14 | 0.23 |
Bodyweight (kg); mean ± SD | 59.63 ± 11.1 | 59 ± 10.1 | 0.84 |
Total duration of disease (months); mean ± SD | 14.4 ± 21.37 | 17.98 ± 20.44 | 0.62 |
Total duration of mucosal disease (months); mean ± SD | 13.46 ± 20.44 | 14.7 ± 25.2 | 0.86 |
Baseline PDAI, mean ± SD | 29 ± 16.4 | 23.6 ± 10.1 | 0.21 |
Site of onset (%) | |||
Mucosa | 19 (86.4) | 15 (68.2) | 0.15 |
Skin | 3 (13.6) | 7 (31.8) | |
Other mucosal involvement (%) | 9/22 (40.9) | 10/22 (45.4) | 1.0 |
History of smoking (%) | 2/22 (9.1) | 1/22 (4.5) | 1.0 |
History of alcohol consumption (%) | 1/22 (4.5) | 1/22 (4.5) | 1.0 |
Previous treatment (%) | |||
Corticosteroids | 18 (81.8) | 19 (86.4) | 0.23 |
Azathioprine | 3 (13.6) | 0 | |
Rituximab | 1 (4.5) | 2 (9.1) | |
Oral antibiotics | 1 (4.5) | 1 (4.5) | |
IVIG | 0 | 1 (4.5) | |
