Table 1 Design of animal experiment (N = 30).

From: Cytochrome P450 2E1 predicts liver functional recovery from donation after circulatory death using air-ventilated normothermic machine perfusion

Group

Harvested liver

Normothermic machine perfusion (NMP)

Perfusate

Control

N = 6

Healthy livers without ischemia

–

–

Hyperoxygenated NMP

N = 6

30 min of in situ warm ischemia followed by 8 h cold ischemia preservation

2 h NMP with oxygen ventilation

–

Air-oxygenated NMP

N = 6

30 min of in situ warm ischemia followed by 8 h cold ischemia preservation

2 h NMP with air ventilation

–

DMSO

N = 4

30 min of in situ warm ischemia followed by 8 h cold ischemia preservation

2 h NMP with air ventilation

DMSO

Rosiglitazone

N = 4

30 min of in situ warm ischemia followed by 8 h cold ischemia preservation

2 h NMP with air ventilation

Rosiglitazone

GW9662

N = 4

30 min of in situ warm ischemia followed by 8 h cold ischemia preservation

2 h NMP with air ventilation

GW9662

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