Figure 4

(a) US images (@7.5 MHz; MI = 0.1) of phantoms (nanodroplets concentration:1.7 × 106–8.4 × 106 NDs/ml) post 1 Gy C-ions exposure (312 MeV/u, 180 mm); (b) Average grayscale value profiles of PVA/PFB NDs phantoms at the different NDs concentrations. The inset plot represents average grey value peak-width (i.e. NDs vaporization signal) as a function of NDs concentration; (c) US images of PVA/PFB NDs phantoms pre- and post-irradiation @ 37 °C with C-ion beam range of 50 mm (150.7 MeV/u, 1 Gy, 4 × 106 ND/ml); (d) Mean derived vaporization profiles from independent phantoms (orange) compared to the pre-irradiation grayscale signal (black). The shaded areas represent the standard deviation (n = 6).