Figure 6 | Scientific Reports

Figure 6

From: Neurophysiological effects of human-derived pathological tau conformers in the APPKM670/671NL.PS1/L166P amyloid mouse model of Alzheimer’s disease

Figure 6

Longitudinal power spectra comparisons and Higuchi fractal dimension score comparisons (a) Log power spectra and accompanying bar plots from 3-month-old animals showing longitudinal change in high gamma power across 5 m.p.i. and treatment-genotype groups. Blue regions indicate the region of the power spectra used for the plotting of bar plots. (b) Bar plot comparisons of 3-month-old and 6-month-old animals for high gamma power. (c) Whole power spectra (1-100 Hz) comparison between 6-month-old animals at 5 m.p.i. and pre-injection. (d) Higuchi fractal dimension score bar plots of the hippocampus of 6-month-old animals at pre-injection, 3 and 5 m.p.i. (m.p.i. refers to months post injection). All bar plots are Mean + SEM. Asterisks indicate significant comparisons (p < 0.05).

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