Figure 3 | Scientific Reports

Figure 3

From: Non-canonical Wnt signaling participates in Jagged1-induced osteo/odontogenic differentiation in human dental pulp stem cells

Figure 3

Dose and time course experiment of Jagged1 promotes Wnt related gene expression in hDPSCs. Correlation of Notch and Wnt pathways. (a) The mRNA levels of Notch-related genes (HES1 and HEY1) and Wnt-related genes (WNT2B, WNT5A, WNT5B, WNT16, DKK1, DKK2, and SOST) were measured using real-time polymerase chain reaction after exposed to different Jagged1 concentrations for 24 h. (b) The mRNA expression of hDPSCs treated with 10 nM Jagged1 was evaluated at day 1, 3, and 7. Bars indicate a significant difference between groups (p < 0.05).

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