Scheme 1
From: Total synthesis and antimicrobial evaluation of (+)-hygrophorone B12 and its analogues

a: Key step in the synthesis of ( +)-hygrophorone B12 (4) by Westermann et al. b: Key step in the synthesis of (−)-6-epi-hygrophorone B14 (6) by Rao et al. c: Key step in the synthesis of (−)-hygrophorone A12 (2) and ( +)-4 by Gholap et al.