Figure 2
From: High-throughput analysis of ANRIL circRNA isoforms in human pancreatic islets
Consistent expression of specific circANRIL isoforms. (A) Exon-specific involvement in back-spliced junctions (top) and fold-change in expression between RNaseR treated and control samples (bottom, normalized for library depth). (B) Frequency of splice site pairing in back-spliced junctions, with proportional usage (top) for each BSJ (bottom), with proportional usage of individual exons on the left. (C) Pairwise Pearson correlations between linear (junction 1–2) and circular ANRIL expression across 122 islet samples. (D) RT-PCR quantification of linear and circular isoforms across 122 islet preparations. (E) Pairwise Pearson correlations (bottom left) and Spearman rank correlations (top right) between linear ANRIL (junction 1–2), circular ANRIL (junction 5–6), CDKN2A isoforms, and CDKN2B abundance across 122 islet preparations.
